In nebuliser therapy, the key question is how much medication reaches the lungs. The droplets the nebuliser produces from the inhalation solution have to be relatively fine to reach the lungs. Droplets ≤ 5 µm are therefore referred to as respirable particles.
The more active substance to reach the lung per minute, the more efficient the inhalation device. There is an objective parameter used to rate efficiency: the Respirable Drug Delivery Rate (RDDR). It describes the respirable dose per minute.
A high RDDR is a sign of an efficient inhalation device. The video explains the RDDR in very simple terms.
Why is the efficiency of an inhalation device so important? The less time it takes for the fine droplets to reach the lungs, the better the inhalation therapy can be integrated into daily routine.
PARI nebulisers have come out top in various comparative studies with commercially available nebulisers for children and adults.1,2
Source: Modified from: Walz-Jung H et al., Pneumologie 2018, 72:820–831
Summary: Ensure the device has a high RDDR. This means short nebulisation times while delivering high doses of the desired medication into the lungs.
PARI nebulisers are often recommended in the package inserts of medications for inhalation. Thanks to their world-wide availability and high quality, our PARI nebulisers are often used in clinical studies of medications.
1 Walz-Jung H et al., Pneumologie 2018
2 Walz-Jung H et al., Poster GPP 2013
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